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Infiltrator is an intuitive network security scanner that can quickly audit computers for vulnerabilities, security holes and exploits, and information enumerations. Infiltrator can reveal security holes and alert the user.
Developer: Infiltration Systems
Free to try; $49.95 to buy | Windows NT/2000/XP
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1 Click Spy Clean your way to maximum security, and protect your computer by detecting and removing different kinds of Adware, Spyware, Malware that represent a great threat to your personal or business environment.
Developer: Secure PC Solutions Inc
Free to try; $29.95 to buy | Windows 98/ME/NT/2000/XP
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Koffix Blocker is a desktop application that helps you to block or restrict sites that are involved in questionable practices. For example, Koffix blocks sites that try to install some sort of spyware, trojan, viruses and worms on...
Developer: Kephyr
Freeware | Windows 98/ME/NT/2000/XP
CRM software for mid-size business. 
A clean registry speeds up your computer! 
Advanced spyware, adware and malware remover 
Software to recover lost photos and images